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br Methods br Results br Discussion ICC represents an aggres
2019-05-04
Methods Results Discussion ICC represents an aggressive malignancy arising from the intrahepatic biliary tree. Recent years have seen a dramatic increase in the incidence of ICC, making it the second most common primary liver cancer. Prognosis of ICC remains poor, with 5-year OS rates rangi
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br Introduction Since Reekers and Bolia introduced
2019-05-04
Introduction Since Reekers and Bolia introduced subintimal angioplasty, the trans-subintimal route has become the preferred technique to advance the guidewire through a totally occluded and often heavily calcified lesion, especially in the aortoiliac segment. The technical failure was seen in 20–
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With respect to the ST elevation in the precordial
2019-05-04
With respect to the ST elevation in the precordial lead, Antzelevitch et al. demonstrated that this can be an order AICAR of early repolarization or J-wave caused by transient outward current (Ito)-mediated transmural differences in the early phases of the action potential. BS is an inherited disea
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br Perioperative risk assessment of thromboembolism The curr
2019-04-30
Perioperative risk assessment of thromboembolism The current thromboembolic risk stratification is largely based on indirect evidence from studies outside of the perioperative setting involving patients with a mechanical ll-37 valve, chronic atrial fibrillation or venous thromboembolism who eith
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Undoubtedly hydroxyurea has a huge potential for improving t
2019-04-30
Undoubtedly, hydroxyurea has a huge potential for improving the quality of lives of people affected by sickle-cell anaemia in settings where frequent and probably unsafe blood transfusions are the current standard of care. However, attention needs to be directed towards the potential adverse effects
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No conviene ignorar la enorme influencia cultural de Estados
2019-04-30
No conviene ignorar la enorme influencia cultural de Estados Unidos en la formación intelectual de Vasconcelos, so pena de caer en contradicciones. Ulises criollo se asienta en una tradición muy estadounidense, la de una fascinación por las cuestiones de la individualidad, la identidad y la autobiog
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br Discussion A familial platelet disorder with
2019-04-30
Discussion A familial platelet disorder with a propensity to myeloid malignancy (FPD/MM) was first reported in 1978 and since then approximately 30 pedigrees with RUNX1 germline mutations have been reported in the literature [9,11]. The RUNX1 gene is composed of 10 exons (1–6, 7A, 7B, 7C and 8).
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br Environmental pollution is a global
2019-04-30
Environmental pollution is a global problem and the subject of increasing worldwide public health concern. In particular, air pollution is regarded as the largest single environmental risk to health. More than 80% of people living in urban areas that monitor air pollution are exposed to air qualit
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br We recently reported associations between maternal age
2019-04-30
We recently reported associations between maternal age at childbirth and outcomes in the offspring, using data from five birth cohorts (COHORTS collaboration) in low-income and middle-income countries (LMICs), in . Young maternal age ( Antimicrobial resistance is recognised as a serious global he
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br Discussion ELT is a well
2019-04-30
Discussion ELT is a well-recognized complication of a dual chamber pacing system.[1,2] This is a wide QRS tachycardia resulting from the sensing of retrograde P-waves by the pacemaker, consequently triggering ventricular pacing beyond the programmed PVARP. Retrograde P-waves are induced by ectopi
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There were differentially expressed genes identified from th
2019-04-30
There were 3151 differentially expressed genes identified from the transcriptome profiling data of 497 patients (Fig. 2). Among these differentially expressed genes, 2190 genes were found to be upregulated in the group with infiltrating lymphocytes ≥1%. As shown in Table 2, these genes were enriched
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I am delighted to introduce the inaugural
2019-04-30
I am delighted to introduce the inaugural issue of . It is very likely that you are reading this online, this being an online-only journal, although we have also printed this first issue in order to showcase the journal to readers of . What is certain is that, in accessing this article, and all the
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Nesta perspectiva enquanto o governo Humalla anunciou uma
2019-04-30
Nesta perspectiva, enquanto o governo Humalla anunciou uma lista de novos projetos mineiros de valor superior ANA 12 Supplier U$ 41 bilhões, dados da Defensoría del Pueblo registraram 210 conflitos sociais em janeiro de 2015 no país, dos quais 140 de natureza socioambiental. Até meados de 2015, cont
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Assim a decis o de avan
2019-04-30
Assim, beta lactamase inhibitor decisão de avançar sobre Lima deve ser entendida antes como uma “fuga para frente” do que como desdobramento de um crescimento orgânico. Mas em seu momento, havia um genuíno receio em relação ao poder insurgente, já que a repercussão das ações senderistas na capital e
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Introduction Acute myeloid leukemia AML is a rare
2019-04-30
Introduction Acute myeloid leukemia (AML) is a rare disease afflicting annually 3–4 persons per 100,000 individuals. With a median age at diagnosis of 67 years, this disease is far more common in the elderly [1]. In this age group, AML has a particularly dismal outcome with less than 5% of the pati
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